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Management of gastric cancer in Asia: resource-stratified guidelines

In The Lancet Oncology
By: Shen L.
Contributor(s): Park SR | Zhang X | Yang HK | Sano T | Yang YH | Yeh KH | Sirohi B | Price T | Hu HM | ShanYS | Kang YK | Fujii M | leochen@nhri.org.tw | Chen LT.
Material type: materialTypeLabelArticleSeries: Vol 14 Issues 12.Publisher: 2013Description: e535-e547.Subject(s): Guidelines | Asia | Mortality | chemotherapy | Management of cancer | Gastric cancer | DDC classification: In: The Lancet OncologySummary: Gastric cancer is the fourth most common cancer globally, and is the second most common cause of death from cancer worldwide. About three-quarters of newly diagnosed cases in 2008 were from Asian countries. With a high mortality-to-incidence ratio, management of gastric cancer is challenging. We discuss evidence for optimum management of gastric cancer in aspects of screening and early detection, diagnosis, and staging; endoscopic and surgical intervention; and the concepts of perioperative, postoperative, and palliative chemotherapy and use of molecularly targeted therapy. Recommendations are formulated on the basis of the framework provided by the Breast Health Global Initiative, using the categories of basic, limited, enhanced, and maximum level. We aim to provide a stepwise strategy for management of gastric cancer applicable to diff erent levels of health-care resources in Asian countries.
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Gastric cancer is the fourth most common cancer globally, and is the second most common cause of death from
cancer worldwide. About three-quarters of newly diagnosed cases in 2008 were from Asian countries. With a high
mortality-to-incidence ratio, management of gastric cancer is challenging. We discuss evidence for optimum
management of gastric cancer in aspects of screening and early detection, diagnosis, and staging; endoscopic and
surgical intervention; and the concepts of perioperative, postoperative, and palliative chemotherapy and use of
molecularly targeted therapy. Recommendations are formulated on the basis of the framework provided by the
Breast Health Global Initiative, using the categories of basic, limited, enhanced, and maximum level. We aim to
provide a stepwise strategy for management of gastric cancer applicable to diff erent levels of health-care resources in
Asian countries.

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